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KMID : 0613820220320110841
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Journal of Life Science
2022 Volume.32 No. 11 p.841 ~ p.846
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Determination of Antioxidant Activities and Bioactive Compounds from Rosa rugosa Extract
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Kim Jun-Hee
Hwang Youn-Sun
Park Jae-Hoon
Kang Min-Ho
Oh Ye-Sol
Kim Jin-Woo
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Abstract
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The purpose of this study was to evaluate the antioxidant properties of Rosa rugosa extract and to identify which of its components are responsible for these properties. Reactive oxygen species play an important role in diseases such as cancer, arteriosclerosis, and heart disease as a consequence of increased metabolic rates, gene mutations, and relative hypoxia. Therefore, the antioxidant effect of R. rugosa extract was confirmed by HPLC, HPLC-MS/MS, the total polyphenol content, the total flavonoid content, and the radical scavenging activity. HPLC and HPLC-MS/MS analyses were con- ducted to identify and quantify the main components of the R. rugosa extract. Gallic acid and epi- gallocatechin gallate were identified as the main components, with 17.4 and 4.35 mg/g dry matter (DM), respectively. The antioxidant activity of R. rugosa extract was evaluated based on its total polyphenol content, total flavonoid content, and radical scavenging activity, which were 72.3 mg gallic acid equivalent/g DM, 11.2 mg quercetin equivalent/g DM, and 87.9%, respectively. The radical scav- enging activities of the main components, gallic acid and epigallocatechin gallate, were 80.5% and
89.7%, respectively. Therefore, R. rugosa has a high polyphenol content and antioxidant activity, and it can be used as a natural antioxidant in food, cosmetics, and pharmaceuticals.
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KEYWORD
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Antioxidant, epigallocatechin gallate, extraction, gallic acid, Rosa rugosa
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